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[Remote] VP of Operations, AI Simulation

Work from home Full-time role Hiring

Note: The job is a remote job and is open to candidates in USA. SandboxAQ is a high-growth company delivering AI solutions that address some of the world's greatest challenges. The VP of Operations will serve as the operational architect for the AI Simulation business unit, driving processes and scaling operational infrastructure to support the BioSim and ChemSim divisions.

Responsibilities

  • Provide operational support and leadership to BioSim and ChemSim divisions, running day-to-day business operations including identifying synergies in resource allocation and operationalizing scaling systems
  • Lead the transition from high-growth experimentation to scaled operations by optimizing talent density and capacity across PhDs, SWEs, and GTM specialists
  • Be responsible for hands-on and end to end execution, track velocity across complex milestones, and rapidly shift resources (financial and talent) as requirements arise and shift
  • Spearhead the Chemical Simulation business unit during its expansion
  • Lead by influence with key partners in Engineering, R&D, Science, GTM, and HR; use forensic root-cause analysis and high EQ to diagnose friction, resolve organizational debt, and ensure team culture remains high-performing and mission-aligned during rapid scaling
  • Manage rigorous trade-off analysis for high-stakes technical investments, ensuring resource allocation is synchronized between divisions and aligned with global revenue triggers

Skills

  • Deep experience in operational leadership, including tenure as a COO, Managing Director, or Head of Ops at venture-backed scaled startups; proven track record of scaling companies from Series B through to mature operations or successful exits
  • Deep familiarity with AI or heavy-compute environments; ability to translate the needs of Research Scientists and Executives into tactical execution against business requirements
  • A 'Builder-Operator' mindset with the ability to pivot instantly from deep-dive spreadsheet/Jira analysis to board-level strategic planning
  • Proven expertise in conducting root-cause analysis on both operational delivery failures and human dynamics (attrition, team friction) within multidisciplinary teams
  • Experience setting up and scaling new business verticals or startup-within-a-startup units
  • A track record of implementing AI/LLM tools to automate internal business functions
  • Experience managing global, remote-first teams through significant organizational change
  • Proven experience navigating complex B2B sales cycles and technical partnerships with Hyperscalers or global industrial leaders
  • Familiarity with Life Sciences (Drug Discovery) or Materials Science (specifically the battery, semiconductor, or metallurgy sectors) and/or direct experience managing programs where the US Government was a primary customer, particularly regarding dual-use technology, national security R&D, or government contracting frameworks

Benefits

  • Comprehensive medical, dental, and vision coverage for employees and dependents with generous employer premium contributions
  • Retirement savings with company matching
  • Paid parental leave
  • Inclusive family-building benefits
  • Flexible paid time off
  • Company-wide seasonal breaks
  • Support for flexible work arrangements that enable sustainable performance
  • Opportunities for continuous learning and growth through on-the-job development, cross-functional collaboration, and access to internal learning and development programs

Company Overview

  • SandboxAQ develops AI and quantum technology solutions that enhance biopharma, cybersecurity, and materials science. It was founded in 2016, and is headquartered in Palo Alto, California, USA, with a workforce of 51-200 employees. Its website is https://www.sandboxaq.com.
  • Company H1B Sponsorship

  • SandboxAQ has a track record of offering H1B sponsorships, with 7 in 2025, 6 in 2024, 3 in 2023, 5 in 2022, 1 in 2021, 5 in 2020. Please note that this does not guarantee sponsorship for this specific role.
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