SeniorEngineerManager- Upstream

Join Amgens Mission of Serving Patients At Amgen, if you feel likeyourepart of something bigger,itsbecause you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980,wevehelped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team,youllhelp make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities thatliewithin them,youllthrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Be part of Amgen's newest and most advanced drug substance manufacturing plant. When completed, the AmgenFleXBatch facility will combine the latest in disposable technologies with traditional stainless-steel equipment to allow for maximum flexibility in operations. TheFleXBatch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027. SeniorEngineerManager- Upstream Live

What You Will Do

Letsdo this.Letschange the world. In this vital role you willbe responsible forthe department capital portfolio andproject management of small capital projects at the drug substance facility inANC.

• Reporting to the Director of Engineering, the Sr Manager will provide technical leadership to a team of manufacturing support engineers supporting commercial production operations with emphasis on Drug Substance bioprocessing equipment.
• Establish clear expectations and prioritiestostaff. Encourage a culture of continuous improvement, partnership, and knowledge sharing.Providedevelopment opportunities, feedback, andactively listen to staff.
• Cultivate a culture of safety ensuring the well-being of all staff members and drive efforts to reduce safety risks.
• Provide technical support to troubleshoot,identifyand resolve process and system issues as needed.
• Be knowledgeable about compliance and regulatory aspects for equipment validation,operationand maintenance.
• Effectively collaborate with key customers and support groups (e.g.Manufacturing, Quality, Process Development, Maintenance, network partners).
• Ensure all tasks and projects areaccomplishedin a safe manner.
• Employ Business Analytics to assess performance andidentifyimprovement opportunities
• Lead Sustainability Program Management of Multi-faceted, Cross-functional,Network Initiative
• Collaborates with leadership to set strategy and businessobjectives.
• Foster andmaintainrelationships with key stakeholders.
• Establish balanced scorecard of strategic and operational key performanceindicators(KPI) in line with industry best practices tomonitor, trend and analyzeequipmentperformance,sustainabilityand reliability programs.
• Ensure action plans areestablishedto address performance gaps or opportunities.
• Communicate gaps andestablishthe proper escalation process to the stakeholders
• Identifyopportunities tooptimizeorganizational efficiency.
• Leads engineering and contractor evaluation and selection process

Win What We Expect Of You We are all different, yet we all use our unique contributions to serve patients. The [vital attribute] professional weseekis a [type of person] with these qualifications. Basic Qualifications

• High school diploma / GED and 12 years of Engineering and/or ProjectManagement experience OR
• Associates degree and 10 years of Engineering and/or Project Management experience OR
• Bachelors degree and 8 years of Engineering and/or Project Management experience OR
• Masters degree and 6 years of Engineering and/or Project Management experience OR
• Doctorate degree and 2 years of Engineering and/or Project Management experience
• Additionally: In addition to meeting at least one of the above requirements, you must have a minimum of 2years experiencedirectly managing people and/or leadership experience leading teams, projects, programs, or directing the allocationorresources. Your managerial experience may run concurrently with the required technical experience referenced above

Preferred Qualifications

• Bachelors degree in chemical engineering or related technicalfield
• 5+ years experience in engineering in a manufacturing support environment with 3+ years experience in the Pharmaceutical or Biotechnology industries
• Demonstrated people management/leadershipexperience
• Experience with Mammalian Cell Culture, ProteinPurification, Clean Utilities, CIP, SIP and Production Services. Upstream unit operation experience such as bioreactor or harvest equipment
• Familiarity designing, troubleshooting, and operating equipment used in cell culture manufacturing including disposabletechnologies
• Experience with Tech Transfer, Process Design, and Commissioning & Qualification
• Experience with validation and change controlmethodology
• Direct experience with regulated environments (i.e., cGMP, OSHA, EPA) including detailed understanding ofcGMPs
• Excellent written and verbal communicationskills
• Demonstrated interpersonal and facilitation skills and ability to work in a collaborative team-basedenvironment
• Ability to apply analytical skills to evaluate and interpret complex problems using multiple sources ofinformation
• Demonstrated ability to lead and influence cross-functional teams and embrace a team-basedculture
• Familiarity with designing and operating equipment used in biopharmaceuticalmanufacturing
• Demonstrated experience in applying Operational Excellence and Lean Manufacturing

Thrive What You Can Expect Of Us As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being. Amgen Offers a Total Rewards Plan Comprising Health And Welfare Plans For Staff And Eligible Dependents, Financial Plans With Opportunities To Save Towards Retirement Or Other Goals, Work/life Balance, And Career Development Opportunities Including

• Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans and bi-annual company-wide shutdowns
• Flexible work models, including remote work arrangements, where possible

Apply nowfor a career that defies imagination Objects in your future are closer than they appear. Join us. careers.amgen.com #AmgenNorthCarolina Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation toparticipatein the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Apply tot his job Apply To this Job